Focus on Pan-Cancer Analysis

The TCGA Pan-Cancer working group has published a set of papers in Nature Publishing Group (NPG) journals exploring the DNA, chromatin and RNA alterations across a diverse set of cancers.  Much of the analysis done by the working group leveraged Synapse services to share and evolve data, results and methodologies while performing integrative analysis, as described in this commentary. There is now a nice summarization of these studies with links to the full papers on the Nature website.

Kudos to the TCGA Pan-Cancer working group for their great research. The Synapse Team is excited to see researchers continue to benefit from their use of the platform. We hope the TCGA Pan-Cancer group can be used as a template for future large-scale collaborative research efforts.


About Brian Bot
I am a Principal Scientist working in Computational Oncology at Sage Bionetworks in Seattle, Washington and Community Manager for our technology platforms. Previously, I worked in the Department of Biomedical Statistics and Informatics at the Mayo Clinic for 7 years. This work included 7 years of dealing with cancer clinical trial data as part of the Mayo Clinic Cancer Center (MCCC). I have extensive experience in working with clinical and genomic data and have a passion for exploring innovative ways to make science more open and transparent. My current work involves both doing innovative research in computational oncology as well as serving as a bridge between biomedical researchers and technology development. At its heart, this work is driven to re-envision how scientists can ensure reproducibility of their research results and communicate complex science to one another and to the public at large. I have been an invited speaker at a number of national and international events to share my experiences living at the intersection of biomedical research and technology.

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